STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SREBF2Sterol regulatory element binding transcription factor 2. (1235 aa)    
Predicted Functional Partners:
SCAP
SREBF chaperone.
   
 0.956
SREBF1
Sterol regulatory element binding transcription factor 1.
  
 
0.925
KPNB1
Karyopherin subunit beta 1.
    
 0.924
MBTPS2
Membrane bound transcription factor peptidase, site 2.
    
 0.879
NPC1
NPC intracellular cholesterol transporter 1.
   
 0.865
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
 
 0.852
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.831
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
 
 0.779
ELOVL6
Elongation of very long chain fatty acids protein.
     
 0.768
MBTPS1
Membrane bound transcription factor peptidase, site 1.
     
 0.742
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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