STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HES3Hes family bHLH transcription factor 3. (185 aa)    
Predicted Functional Partners:
HEY2
Hes related family bHLH transcription factor with YRPW motif 2.
      
 0.583
ISM1
Isthmin 1.
   
  
 0.572
HEY1
Hes related family bHLH transcription factor with YRPW motif 1.
      
 0.519
NOTCH3
Notch receptor 3.
   
 0.506
FEZF1
FEZ family zinc finger 1.
    
 
 0.484
PTPN14
Protein tyrosine phosphatase non-receptor type 14.
      
 0.480
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.479
UCN3
Urocortin 3.
      
 0.470
EXOSC2
Exosome component 2.
      
 0.468
EVX1
Even-skipped homeobox 1.
      
 0.442
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.