STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6RL85_HORSEIg-like domain-containing protein. (152 aa)    
Predicted Functional Partners:
OR10G3
Olfactory receptor family 10 subfamily G member 3.
    
 
 0.687
TOX4
TOX high mobility group box family member 4.
      
 0.670
ENSECAP00000030128
Ig-like domain-containing protein.
   
  0.668
ENSECAP00000033309
Ig-like domain-containing protein.
  
   
 0.595
F6PJ59_HORSE
Ig-like domain-containing protein.
  
 0.568
RNF212B
Ring finger protein 212B.
      
 0.564
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
      
 0.556
ENSECAP00000031862
Ig-like domain-containing protein.
  
 
 0.512
RNF212
RING-type domain-containing protein.
      
 0.489
CHD8
Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]
   
  
 0.472
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.