node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQP2 | AVP | ENSECAP00000021228 | ENSECAP00000022402 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | 0.696 |
AQP2 | AVPR2 | ENSECAP00000021228 | ENSECAP00000020416 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.820 |
AVP | AQP2 | ENSECAP00000022402 | ENSECAP00000021228 | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.696 |
AVP | AVPR1A | ENSECAP00000022402 | ENSECAP00000008330 | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | 0.990 |
AVP | AVPR1B | ENSECAP00000022402 | ENSECAP00000011404 | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.909 |
AVP | AVPR2 | ENSECAP00000022402 | ENSECAP00000020416 | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.978 |
AVP | GPR150 | ENSECAP00000022402 | ENSECAP00000032651 | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | G protein-coupled receptor 150. | 0.674 |
AVP | GPR19 | ENSECAP00000022402 | ENSECAP00000020921 | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | G protein-coupled receptor 19. | 0.619 |
AVP | GRK2 | ENSECAP00000022402 | ENSECAP00000029787 | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.742 |
AVP | NPSR1 | ENSECAP00000022402 | ENSECAP00000010898 | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.628 |
AVP | OXT | ENSECAP00000022402 | ENSECAP00000044610 | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | Oxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family. | 0.787 |
AVP | OXTR | ENSECAP00000022402 | ENSECAP00000015419 | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.785 |
AVPR1A | AVP | ENSECAP00000008330 | ENSECAP00000022402 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | 0.990 |
AVPR1A | AVPR1B | ENSECAP00000008330 | ENSECAP00000011404 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.940 |
AVPR1A | AVPR2 | ENSECAP00000008330 | ENSECAP00000020416 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.925 |
AVPR1A | GRK2 | ENSECAP00000008330 | ENSECAP00000029787 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.524 |
AVPR1A | OXT | ENSECAP00000008330 | ENSECAP00000044610 | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | Oxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family. | 0.808 |
AVPR1B | AVP | ENSECAP00000011404 | ENSECAP00000022402 | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Neurophysin 2; Neurophysin 2 specifically binds the midbrain peptide hormone vasopressin; Belongs to the vasopressin/oxytocin family. | 0.909 |
AVPR1B | AVPR1A | ENSECAP00000011404 | ENSECAP00000008330 | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. | 0.940 |
AVPR1B | AVPR2 | ENSECAP00000011404 | ENSECAP00000020416 | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.918 |