STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDCP1CUB domain containing protein 1. (836 aa)    
Predicted Functional Partners:
EPHA2
EPH receptor A2.
   
 
 0.562
PRKCD
Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 
 0.522
CLK1
CDC like kinase 1.
      
 0.510
SRC
Tyrosine-protein kinase.
   
 
 0.499
EGFR
Receptor protein-tyrosine kinase.
    
 
 0.496
ALCAM
Activated leukocyte cell adhesion molecule.
  
  
 0.480
POLR1E
RNA polymerase I subunit E.
      
 0.476
C1R
Complement C1r; Belongs to the peptidase S1 family.
      
 0.473
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
      
 0.444
ZBTB7B
Zinc finger and BTB domain containing 7B.
   
  
 0.404
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.