STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELF4E74 like ETS transcription factor 4. (662 aa)    
Predicted Functional Partners:
LRRC30
Leucine rich repeat containing 30.
      
 0.715
TBK1
TANK binding kinase 1.
    
 0.648
SYCP2
Synaptonemal complex protein 2.
   
  
 0.581
MAVS
Mitochondrial antiviral signaling protein.
  
 
 
 0.578
ZMYM6
Zinc finger MYM-type containing 6.
      
 0.539
INSR
Tyrosine-protein kinase receptor.
    
 0.538
ESPNL
Espin like.
    
 
 0.492
RUNX3
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
   
 0.492
UBXN1
UBX domain protein 1.
   
  
 0.483
PRR7
Proline rich 7, synaptic.
      
 0.476
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (14%) [HD]