ADAMTS3 protein (Equus caballus) - STRING interaction network

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Score

ADAMTS3

ADAM metallopeptidase with thrombospondin type 1 motif 3. (1201 aa)

Predicted Functional Partners:

CCBE1

0.844

TMEM86A

0.801

GET3

0.732

VEGFC

0.717

VIPR1

0.591

SVEP1

0.571

SCUBE3

0.548

TSPAN2

0.543

LOX

0.532

CX3CL1

0.532

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTS3	CCBE1	ENSECAP00000023072	ENSECAP00000039097	ADAM metallopeptidase with thrombospondin type 1 motif 3.	Collagen and calcium binding EGF domains 1.	0.844
ADAMTS3	CX3CL1	ENSECAP00000023072	ENSECAP00000037564	ADAM metallopeptidase with thrombospondin type 1 motif 3.	SCY domain-containing protein.	0.532
ADAMTS3	GET3	ENSECAP00000023072	ENSECAP00000005353	ADAM metallopeptidase with thrombospondin type 1 motif 3.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.732
ADAMTS3	LOX	ENSECAP00000023072	ENSECAP00000012463	ADAM metallopeptidase with thrombospondin type 1 motif 3.	Lysyl oxidase.	0.532
ADAMTS3	SCUBE3	ENSECAP00000023072	ENSECAP00000014029	ADAM metallopeptidase with thrombospondin type 1 motif 3.	Signal peptide, CUB domain and EGF like domain containing 3.	0.548
ADAMTS3	SVEP1	ENSECAP00000023072	ENSECAP00000019725	ADAM metallopeptidase with thrombospondin type 1 motif 3.	Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1.	0.571
ADAMTS3	TMEM86A	ENSECAP00000023072	ENSECAP00000051024	ADAM metallopeptidase with thrombospondin type 1 motif 3.	Transmembrane protein 86A.	0.801
ADAMTS3	TSPAN2	ENSECAP00000023072	ENSECAP00000008919	ADAM metallopeptidase with thrombospondin type 1 motif 3.	Tetraspanin.	0.543
ADAMTS3	VEGFC	ENSECAP00000023072	ENSECAP00000038962	ADAM metallopeptidase with thrombospondin type 1 motif 3.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.717
ADAMTS3	VIPR1	ENSECAP00000023072	ENSECAP00000045304	ADAM metallopeptidase with thrombospondin type 1 motif 3.	Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family.	0.591
CCBE1	ADAMTS3	ENSECAP00000039097	ENSECAP00000023072	Collagen and calcium binding EGF domains 1.	ADAM metallopeptidase with thrombospondin type 1 motif 3.	0.844
CCBE1	SVEP1	ENSECAP00000039097	ENSECAP00000019725	Collagen and calcium binding EGF domains 1.	Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1.	0.493
CCBE1	VEGFC	ENSECAP00000039097	ENSECAP00000038962	Collagen and calcium binding EGF domains 1.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.814
CX3CL1	ADAMTS3	ENSECAP00000037564	ENSECAP00000023072	SCY domain-containing protein.	ADAM metallopeptidase with thrombospondin type 1 motif 3.	0.532
CX3CL1	GET3	ENSECAP00000037564	ENSECAP00000005353	SCY domain-containing protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.407
CX3CL1	TMEM86A	ENSECAP00000037564	ENSECAP00000051024	SCY domain-containing protein.	Transmembrane protein 86A.	0.471
CX3CL1	VIPR1	ENSECAP00000037564	ENSECAP00000045304	SCY domain-containing protein.	Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family.	0.476
GET3	ADAMTS3	ENSECAP00000005353	ENSECAP00000023072	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	ADAM metallopeptidase with thrombospondin type 1 motif 3.	0.732
GET3	CX3CL1	ENSECAP00000005353	ENSECAP00000037564	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	SCY domain-containing protein.	0.407
GET3	TMEM86A	ENSECAP00000005353	ENSECAP00000051024	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Transmembrane protein 86A.	0.883