STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2AC16Histone H2A; Belongs to the histone H2A family. (158 aa)    
Predicted Functional Partners:
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.837
LOC102148494
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.784
LOC100054332
Histone H4.
 
 
 0.784
LOC100630823
Histone H4.
 
 
 0.784
SMARCB1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.
    
 
 0.778
H2BC18
Histone H2B; Belongs to the histone H2B family.
 
 0.719
LOC100068321
Histone H2B; Belongs to the histone H2B family.
 
 0.715
LOC100053695
Histone H2B; Belongs to the histone H2B family.
 
 0.715
LOC100068222
Histone H2B; Belongs to the histone H2B family.
 
 0.715
LOC100053499
Histone H2B type 1.
 
 0.715
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.