node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APRT | LOC100065392 | ENSECAP00000022806 | ENSECAP00000023848 | Adenine phosphoribosyltransferase. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.808 |
APRT | MRI1 | ENSECAP00000022806 | ENSECAP00000008708 | Adenine phosphoribosyltransferase. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.483 |
APRT | NT5E | ENSECAP00000022806 | ENSECAP00000007576 | Adenine phosphoribosyltransferase. | 5'-nucleotidase ecto. | 0.502 |
APRT | UPP1 | ENSECAP00000022806 | ENSECAP00000036700 | Adenine phosphoribosyltransferase. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.865 |
CDKAL1 | LOC100065392 | ENSECAP00000022470 | ENSECAP00000023848 | CDK5 regulatory subunit associated protein 1 like 1. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.662 |
CDKN2A | CDKN2B | ENSECAP00000054966 | ENSECAP00000016076 | Cyclin dependent kinase inhibitor 2A. | Cyclin dependent kinase inhibitor 2B. | 0.905 |
CDKN2A | LOC100065392 | ENSECAP00000054966 | ENSECAP00000023848 | Cyclin dependent kinase inhibitor 2A. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.573 |
CDKN2B | CDKN2A | ENSECAP00000016076 | ENSECAP00000054966 | Cyclin dependent kinase inhibitor 2B. | Cyclin dependent kinase inhibitor 2A. | 0.905 |
CDKN2B | LOC100065392 | ENSECAP00000016076 | ENSECAP00000023848 | Cyclin dependent kinase inhibitor 2B. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.701 |
EPHX2 | LOC100065392 | ENSECAP00000021131 | ENSECAP00000023848 | Epoxide hydrolase 2. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.871 |
EPHX2 | NT5E | ENSECAP00000021131 | ENSECAP00000007576 | Epoxide hydrolase 2. | 5'-nucleotidase ecto. | 0.789 |
LOC100065392 | APRT | ENSECAP00000023848 | ENSECAP00000022806 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Adenine phosphoribosyltransferase. | 0.808 |
LOC100065392 | CDKAL1 | ENSECAP00000023848 | ENSECAP00000022470 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | CDK5 regulatory subunit associated protein 1 like 1. | 0.662 |
LOC100065392 | CDKN2A | ENSECAP00000023848 | ENSECAP00000054966 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Cyclin dependent kinase inhibitor 2A. | 0.573 |
LOC100065392 | CDKN2B | ENSECAP00000023848 | ENSECAP00000016076 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Cyclin dependent kinase inhibitor 2B. | 0.701 |
LOC100065392 | EPHX2 | ENSECAP00000023848 | ENSECAP00000021131 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Epoxide hydrolase 2. | 0.871 |
LOC100065392 | MRI1 | ENSECAP00000023848 | ENSECAP00000008708 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.964 |
LOC100065392 | NT5E | ENSECAP00000023848 | ENSECAP00000007576 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 5'-nucleotidase ecto. | 0.618 |
LOC100065392 | SMS | ENSECAP00000023848 | ENSECAP00000015338 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Spermine synthase. | 0.961 |
LOC100065392 | SRM | ENSECAP00000023848 | ENSECAP00000017331 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Spermidine synthase; Belongs to the spermidine/spermine synthase family. | 0.963 |