STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRAF4TNF receptor-associated factor. (470 aa)    
Predicted Functional Partners:
TRADD
TNFRSF1A associated via death domain.
   
 0.724
BIRC6
Baculoviral IAP repeat containing 6.
    
 0.690
IRAK2
Interleukin 1 receptor associated kinase 2.
   
 0.657
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.648
IRAK4
Interleukin 1 receptor associated kinase 4.
   
 0.647
ERN2
Endoplasmic reticulum to nucleus signaling 2.
   
 0.641
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.620
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.612
IRAK3
Interleukin 1 receptor associated kinase 3.
   
 0.608
TANK
TRAF family member associated NFKB activator.
    
 0.607
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.