PDZRN3 protein (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PDZRN3

PDZ domain containing ring finger 3. (1066 aa)

Predicted Functional Partners:

SHQ1

0.808

GXYLT2

0.765

BIRC6

0.721

RANGRF

0.719

UBOX5

0.719

LONP2

0.719

FCHSD2

0.716

OSBP2

0.691

EBPL

0.681

MUSK

0.674

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIRC6	MUSK	ENSECAP00000017955	ENSECAP00000008277	Baculoviral IAP repeat containing 6.	Muscle associated receptor tyrosine kinase.	0.411
BIRC6	PDZRN3	ENSECAP00000017955	ENSECAP00000024971	Baculoviral IAP repeat containing 6.	PDZ domain containing ring finger 3.	0.721
BIRC6	UBOX5	ENSECAP00000017955	ENSECAP00000025015	Baculoviral IAP repeat containing 6.	U-box domain containing 5.	0.431
EBPL	PDZRN3	ENSECAP00000018707	ENSECAP00000024971	EBP like.	PDZ domain containing ring finger 3.	0.681
FCHSD2	LONP2	ENSECAP00000009144	ENSECAP00000054296	FCH and double SH3 domains 2.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	0.720
FCHSD2	PDZRN3	ENSECAP00000009144	ENSECAP00000024971	FCH and double SH3 domains 2.	PDZ domain containing ring finger 3.	0.716
FCHSD2	RANGRF	ENSECAP00000009144	ENSECAP00000012960	FCH and double SH3 domains 2.	RAN guanine nucleotide release factor.	0.716
FCHSD2	SHQ1	ENSECAP00000009144	ENSECAP00000013366	FCH and double SH3 domains 2.	SHQ1, H/ACA ribonucleoprotein assembly factor.	0.680
FCHSD2	UBOX5	ENSECAP00000009144	ENSECAP00000025015	FCH and double SH3 domains 2.	U-box domain containing 5.	0.716
GXYLT2	OSBP2	ENSECAP00000023727	ENSECAP00000013111	Glucoside xylosyltransferase 2.	Oxysterol-binding protein; Belongs to the OSBP family.	0.907
GXYLT2	PDZRN3	ENSECAP00000023727	ENSECAP00000024971	Glucoside xylosyltransferase 2.	PDZ domain containing ring finger 3.	0.765
GXYLT2	SHQ1	ENSECAP00000023727	ENSECAP00000013366	Glucoside xylosyltransferase 2.	SHQ1, H/ACA ribonucleoprotein assembly factor.	0.803
LONP2	FCHSD2	ENSECAP00000054296	ENSECAP00000009144	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	FCH and double SH3 domains 2.	0.720
LONP2	PDZRN3	ENSECAP00000054296	ENSECAP00000024971	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	PDZ domain containing ring finger 3.	0.719
LONP2	RANGRF	ENSECAP00000054296	ENSECAP00000012960	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	RAN guanine nucleotide release factor.	0.721
LONP2	SHQ1	ENSECAP00000054296	ENSECAP00000013366	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	SHQ1, H/ACA ribonucleoprotein assembly factor.	0.672
LONP2	UBOX5	ENSECAP00000054296	ENSECAP00000025015	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	U-box domain containing 5.	0.722
MUSK	BIRC6	ENSECAP00000008277	ENSECAP00000017955	Muscle associated receptor tyrosine kinase.	Baculoviral IAP repeat containing 6.	0.411
MUSK	PDZRN3	ENSECAP00000008277	ENSECAP00000024971	Muscle associated receptor tyrosine kinase.	PDZ domain containing ring finger 3.	0.674
OSBP2	GXYLT2	ENSECAP00000013111	ENSECAP00000023727	Oxysterol-binding protein; Belongs to the OSBP family.	Glucoside xylosyltransferase 2.	0.907