STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (646 aa)    
Predicted Functional Partners:
ENO1
Uncharacterized protein.
   
 
 0.964
ENO3
Enolase 3.
     
 0.958
MDH1
Malate dehydrogenase.
  
 
 0.957
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.955
MDH2
Malate dehydrogenase.
  
 
 0.954
ENO2
Enolase 2.
   
 
 0.948
ENO4
Enolase 4.
     
 0.947
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.946
CS
Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.936
ACLY
ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
   
 
 0.932
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.