STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGIF2LXHomeobox domain-containing protein. (237 aa)    
Predicted Functional Partners:
PBX2
PBX homeobox 2.
    
 0.497
PBX1
PBX homeobox 1.
    
 0.497
PBX3
PBX homeobox 3.
    
 0.497
PPIG
Peptidylprolyl isomerase G.
   
  
 0.490
SMAD2
Mothers against decapentaplegic homolog.
    
 0.476
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.466
VGLL4
Vestigial like family member 4.
      
 0.461
SMAD4
Mothers against decapentaplegic homolog.
    
 0.444
HHEX
Hematopoietically expressed homeobox.
   
 
 0.417
SMAD3
Mothers against decapentaplegic homolog.
    
 0.417
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.