STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F11RF11 receptor. (307 aa)    
Predicted Functional Partners:
ITGAL
Integrin subunit alpha L; Belongs to the integrin alpha chain family.
   
 0.958
TJP2
Tight junction protein 2; Belongs to the MAGUK family.
   
 0.955
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
   
 0.955
PARD3
Par-3 family cell polarity regulator.
   
 0.951
ITGB2
Integrin beta.
   
 
 0.946
RAPGEF6
Uncharacterized protein.
     
 0.930
JAM2
Junctional adhesion molecule 2.
    
0.927
OCLN
Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family.
   
 
 0.926
CGN
Cingulin.
   
 
 0.925
JAM3
Junctional adhesion molecule 3.
    
0.917
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.