STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEK2Pleckstrin 2. (362 aa)    
Predicted Functional Partners:
OSBP
Oxysterol binding protein.
   
  
 0.830
CDC42
Cell division control protein 42-like protein.
   
 
 0.827
SRC
Tyrosine-protein kinase.
   
  
 0.755
BTK
Tyrosine-protein kinase.
   
  
 0.754
RABIF
RAB interacting factor.
   
  
 0.730
BIN1
Bridging integrator 1.
   
 
 0.706
PLCD1
Phosphoinositide phospholipase C.
      
 0.686
CYTH4
Cytohesin 4.
   
  
 0.655
PTEN
Phosphatase and tensin homolog.
      
 0.646
PLEKHM1
Pleckstrin homology and RUN domain containing M1.
   
  
 0.622
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.