STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSECAP00000025939J domain-containing protein. (222 aa)    
Predicted Functional Partners:
HSPA5
Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.
 
 0.751
HSPA9
Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.
 
 0.741
HSPA8-2
Heat shock cognate 71 kDa protein; Belongs to the heat shock protein 70 family.
 
 0.693
HSPA8
Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...]
 
 0.691
HSPA4L
Heat shock protein family A (Hsp70) member 4 like.
 
 0.686
LOC111769297
Uncharacterized protein.
 
 0.680
HSPA1L
Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family.
 
 0.679
HSPA1A
Uncharacterized protein; Belongs to the heat shock protein 70 family.
 
 0.679
HSPH1
Heat shock protein family H (Hsp110) member 1.
 
 0.678
HSPA14
Heat shock protein family A (Hsp70) member 14.
 
 0.676
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.