STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASAH1Uncharacterized protein; Belongs to the acid ceramidase family. (405 aa)    
Predicted Functional Partners:
SCARB2
Scavenger receptor class B member 2; Belongs to the CD36 family.
   
 
 0.674
SGPL1
Sphingosine-1-phosphate lyase 1.
      
 0.667
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
   
 
 0.665
MAN2B1
Alpha-mannosidase.
    
 
 0.651
ACER3
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
   
  
 0.611
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
 0.602
GNPTAB
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta.
    
 
 0.599
GBA2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
    
 0.598
GBA
Glucosylceramidase.
   
  
 0.586
SPTLC2
Serine palmitoyltransferase long chain base subunit 2.
      
 0.582
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.