STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKN1Protein kinase N1. (1098 aa)    
Predicted Functional Partners:
RHOA
Transforming protein RhoA-like protein.
   
 0.981
PDPK1
3-phosphoinositide dependent protein kinase 1.
    
0.976
PKN2
Protein kinase N2.
  
 
0.934
NCOA2
Nuclear receptor coactivator.
   
 
 0.926
MEFV
MEFV innate immuity regulator, pyrin.
    
 0.923
CDC25C
Cell division cycle 25C.
    
 0.911
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.
    
 0.887
AR
Androgen receptor.
   
 0.826
RHOB
Ras homolog family member B.
   
 0.794
PPP1R14A
Protein phosphatase 1 regulatory inhibitor subunit 14A.
    
 0.726
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.