STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQP8Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)    
Predicted Functional Partners:
AQP7
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
 0.976
AQP11
Aquaporin-11; Channel protein that facilitates the transport of water, glycerol and hydrogen peroxide across membrane of cell or organelles guaranteeing intracellular homeostasis in several organes like liver, kidney and brain. In situation of stress, participates in endoplasmic reticulum (ER) homeostasis by regulating redox homeostasis through the transport of hydrogen peroxide across the endoplasmic reticulum membrane thereby regulating the oxidative stress through the NADPH oxidase 2 pathway (By similarity). Plays a role by maintaining an environment suitable for translation or prot [...]
     
 0.973
AQP10
Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.883
AQP3
Aquaporin 3; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.756
AQP9
Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
0.750
LCMT1
Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.
 
 
  
 0.744
AQP4
Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.707
AQP1
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.697
AQP6
Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.608
LOC111774741
Solute carrier family 14 member 2.
   
  
 0.605
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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