STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSZCathepsin Z; Belongs to the peptidase C1 family. (347 aa)    
Predicted Functional Partners:
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 
 0.903
BCL2L1
BCL2 like 1.
   
 
 0.903
AGT
Angiotensinogen; Belongs to the serpin family.
    
 0.810
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
   
 0.762
LGMN
Legumain.
   
 
 0.744
MCFD2
Multiple coagulation factor deficiency 2.
     
 0.733
GRN
Antimicrobial peptide eNAP-1; Has antimicrobial activity against Gram-negative and Gram- positive bacteria; Belongs to the granulin family.
   
 0.723
CTSD
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.697
BIRC5
Baculoviral IAP repeat containing 5.
     
 0.690
PSAP
Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
   
 
 0.677
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.