STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF1Rho guanine nucleotide exchange factor 1. (1040 aa)    
Predicted Functional Partners:
GNA13
G protein subunit alpha 13.
   
 0.998
RHOA
Transforming protein RhoA-like protein.
   
 0.986
GNA12
G protein subunit alpha 12.
    
 0.981
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
   
 0.961
ARHGEF11
Rho guanine nucleotide exchange factor 11.
   
 
0.938
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.936
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.936
AKAP13
A-kinase anchoring protein 13.
   
0.936
ARHGEF7
Rho guanine nucleotide exchange factor 7.
   
 0.936
ARHGEF12
Rho guanine nucleotide exchange factor 12.
  
  
0.933
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.