STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPDYAUncharacterized protein. (311 aa)    
Predicted Functional Partners:
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.934
CDC25C
Cell division cycle 25C.
     
  0.900
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.797
NFYB
Nuclear transcription factor Y subunit beta; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors (By similarity).
   
 0.758
NFYA
Nuclear transcription factor Y subunit alpha.
    
 0.749
F6XTK8_HORSE
CBFD_NFYB_HMF domain-containing protein.
    
 0.717
SUN1
Sad1 and UNC84 domain containing 1.
    
 
 0.611
CDK3
Cyclin dependent kinase 3; Belongs to the protein kinase superfamily.
   
 0.582
CDKN1B
Cyclin dependent kinase inhibitor 1B.
    
 
 0.531
CDKN1C
Cyclin dependent kinase inhibitor 1C.
    
 
 0.531
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.