SLC2A5 protein (Equus caballus) - STRING interaction network

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SLC2A5

Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake. (514 aa)

Predicted Functional Partners:

SLC5A1

0.867

KHK

0.752

SLC5A10

0.709

SLC1A4

0.696

SLC43A2

0.653

SLC7A2

0.644

GPR157

0.598

SLC5A11

0.548

LCTL

0.529

SLC1A5

0.525

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPR157	SLC2A5	ENSECAP00000019103	ENSECAP00000027324	G protein-coupled receptor 157.	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	0.598
KHK	SLC2A5	ENSECAP00000044514	ENSECAP00000027324	Ketohexokinase.	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	0.752
LCTL	SLC2A5	ENSECAP00000012054	ENSECAP00000027324	Lactase like; Belongs to the glycosyl hydrolase 1 family.	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	0.529
SLC1A4	SLC2A5	ENSECAP00000009506	ENSECAP00000027324	Solute carrier family 1 member 4.	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	0.696
SLC1A4	SLC43A2	ENSECAP00000009506	ENSECAP00000048037	Solute carrier family 1 member 4.	Solute carrier family 43 member 2.	0.794
SLC1A4	SLC5A1	ENSECAP00000009506	ENSECAP00000001706	Solute carrier family 1 member 4.	Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.585
SLC1A4	SLC5A11	ENSECAP00000009506	ENSECAP00000003975	Solute carrier family 1 member 4.	Solute carrier family 5 member 11; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.712
SLC1A4	SLC7A2	ENSECAP00000009506	ENSECAP00000049576	Solute carrier family 1 member 4.	Solute carrier family 7 member 2.	0.710
SLC1A5	SLC2A5	ENSECAP00000009592	ENSECAP00000027324	Amino acid transporter.	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	0.525
SLC1A5	SLC43A2	ENSECAP00000009592	ENSECAP00000048037	Amino acid transporter.	Solute carrier family 43 member 2.	0.651
SLC1A5	SLC5A1	ENSECAP00000009592	ENSECAP00000001706	Amino acid transporter.	Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.620
SLC1A5	SLC5A10	ENSECAP00000009592	ENSECAP00000012586	Amino acid transporter.	Solute carrier family 5 member 10; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.554
SLC1A5	SLC5A11	ENSECAP00000009592	ENSECAP00000003975	Amino acid transporter.	Solute carrier family 5 member 11; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.504
SLC1A5	SLC7A2	ENSECAP00000009592	ENSECAP00000049576	Amino acid transporter.	Solute carrier family 7 member 2.	0.724
SLC2A5	GPR157	ENSECAP00000027324	ENSECAP00000019103	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	G protein-coupled receptor 157.	0.598
SLC2A5	KHK	ENSECAP00000027324	ENSECAP00000044514	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	Ketohexokinase.	0.752
SLC2A5	LCTL	ENSECAP00000027324	ENSECAP00000012054	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	Lactase like; Belongs to the glycosyl hydrolase 1 family.	0.529
SLC2A5	SLC1A4	ENSECAP00000027324	ENSECAP00000009506	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	Solute carrier family 1 member 4.	0.696
SLC2A5	SLC1A5	ENSECAP00000027324	ENSECAP00000009592	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	Amino acid transporter.	0.525
SLC2A5	SLC43A2	ENSECAP00000027324	ENSECAP00000048037	Solute carrier family 2, facilitated glucose transporter member 5; Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.	Solute carrier family 43 member 2.	0.653

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