STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDF1Rhomboid 5 homolog 1. (891 aa)    
Predicted Functional Partners:
SSR2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
   
  
 0.685
PCDH18
Protocadherin 18.
   
 
 0.652
ADAM17
ADAM metallopeptidase domain 17.
    
 0.636
PRPSAP1
Phosphoribosyl pyrophosphate synthetase associated protein 1.
   
  
 0.565
METTL23
Methyltransferase like 23.
    
 
 0.557
AANAT
Aralkylamine N-acetyltransferase.
      
 0.489
MPG
N-methylpurine DNA glycosylase.
  
  
 0.484
RHBDL2
Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
    
 
0.482
HBA
Hemoglobin subunit theta-1; Belongs to the globin family.
   
  
 0.479
HVCN1
Hydrogen voltage gated channel 1.
   
 
 0.478
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.