STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSECAP00000027821Galectin. (159 aa)    
Predicted Functional Partners:
HAVCR2
Hepatitis A virus cellular receptor 2.
    
 0.742
TIGIT
T cell immunoreceptor with Ig and ITIM domains.
      
 0.627
CD4
CD4 molecule.
   
 0.552
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
      
 0.535
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.
   
  
 0.525
CD44
CD44 antigen.
   
 
 0.515
USP18
USP domain-containing protein; Belongs to the peptidase C19 family.
   
  
 0.472
BTLA
B and T lymphocyte associated.
      
 0.465
CD274
CD274 molecule.
   
  
 0.456
GALM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
      
 0.445
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.