STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC10Histone deacetylase 10. (716 aa)    
Predicted Functional Partners:
ARID4B
AT-rich interaction domain 4B.
    
 0.792
ARID4A
AT-rich interaction domain 4A.
    
 0.792
H2AZ2
Histone H2A; Belongs to the histone H2A family.
   
 0.787
H2AZ1
Histone H2A; Belongs to the histone H2A family.
   
 0.787
HDAC8
Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
  
 
0.785
H2AFY2
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
    
 0.764
H2BC1
Histone H2B; Belongs to the histone H2B family.
    
 0.739
H2BC11
Histone H2B; Belongs to the histone H2B family.
    
 0.735
H2AX
Histone H2A; Belongs to the histone H2A family.
    
 0.735
H2BC3
Histone H2B; Belongs to the histone H2B family.
    
 0.735
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.