STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P2RY8P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (440 aa)    
Predicted Functional Partners:
S1PR2
Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.734
PLCXD1
Phosphatidylinositol specific phospholipase C X domain containing 1.
      
 0.692
SPRY3
Sprouty RTK signaling antagonist 3.
      
 0.676
SHOX
Short stature homeobox.
     
 0.634
CD180
CD180 molecule.
    
 0.583
ARHGEF1
Rho guanine nucleotide exchange factor 1.
      
 0.575
IL9R
Interleukin 9 receptor.
      
 0.540
LPAR2
Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
 0.501
GNA13
G protein subunit alpha 13.
    
 0.495
MXRA5
Matrix remodeling associated 5.
    
 0.487
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.