STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP4K3Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (894 aa)    
Predicted Functional Partners:
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
   
0.915
TSPAN18
Tetraspanin.
   
  
 0.685
ZBTB37
Zinc finger and BTB domain containing 37.
      
 0.635
ADCY4
Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
 
    
 0.608
IPMK
Kinase; Belongs to the inositol phosphokinase (IPK) family.
   
  
 0.576
MIOS
Meiosis regulator for oocyte development.
   
  
 0.539
SH3BP4
SH3 domain binding protein 4.
      
 0.535
TMEM178A
Transmembrane protein 178A.
      
 0.518
WDR59
WD repeat domain 59.
      
 0.516
RHEB
Uncharacterized protein; Belongs to the beta/gamma-crystallin family.
     
 0.513
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (12%) [HD]