LOC100067994 protein (Equus caballus) - STRING interaction network

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Score

LOC100067994

UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)

Predicted Functional Partners:

COMT

0.947

CYP1B1

0.946

CYP1A1

0.936

UGDH

0.931

SULT1E1

0.919

AKR1D1

0.907

HSD11B1

0.906

HAO2

0.906

GUSB

0.905

BLVRA

0.904

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKR1D1	HAO2	ENSECAP00000009863	ENSECAP00000028931	Aldo-keto reductase family 1 member D1.	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.	0.938
AKR1D1	HSD11B1	ENSECAP00000009863	ENSECAP00000016873	Aldo-keto reductase family 1 member D1.	Hydroxysteroid 11-beta dehydrogenase 1.	0.923
AKR1D1	LOC100067994	ENSECAP00000009863	ENSECAP00000029191	Aldo-keto reductase family 1 member D1.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.907
BLVRA	LOC100067994	ENSECAP00000033526	ENSECAP00000029191	Biliverdin reductase A.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.904
COMT	CYP1A1	ENSECAP00000047104	ENSECAP00000012229	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	0.970
COMT	CYP1B1	ENSECAP00000047104	ENSECAP00000017028	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.979
COMT	LOC100067994	ENSECAP00000047104	ENSECAP00000029191	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.947
COMT	SULT1E1	ENSECAP00000047104	ENSECAP00000052928	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.435
CYP1A1	COMT	ENSECAP00000012229	ENSECAP00000047104	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	0.970
CYP1A1	CYP1B1	ENSECAP00000012229	ENSECAP00000017028	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.939
CYP1A1	HAO2	ENSECAP00000012229	ENSECAP00000028931	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.	0.945
CYP1A1	HSD11B1	ENSECAP00000012229	ENSECAP00000016873	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	Hydroxysteroid 11-beta dehydrogenase 1.	0.921
CYP1A1	LOC100067994	ENSECAP00000012229	ENSECAP00000029191	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.936
CYP1A1	SULT1E1	ENSECAP00000012229	ENSECAP00000052928	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.938
CYP1B1	COMT	ENSECAP00000017028	ENSECAP00000047104	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	0.979
CYP1B1	CYP1A1	ENSECAP00000017028	ENSECAP00000012229	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	0.939
CYP1B1	HAO2	ENSECAP00000017028	ENSECAP00000028931	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.	0.451
CYP1B1	LOC100067994	ENSECAP00000017028	ENSECAP00000029191	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.946
GUSB	LOC100067994	ENSECAP00000012672	ENSECAP00000029191	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.905
HAO2	AKR1D1	ENSECAP00000028931	ENSECAP00000009863	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.	Aldo-keto reductase family 1 member D1.	0.938