PPA2 protein (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PPA2

Pyrophosphatase (inorganic) 2. (366 aa)

Predicted Functional Partners:

APRT

0.807

PAIP2

0.770

ATP6V0A2

0.739

EEF1G

0.735

EIF5A

0.703

EIF5A2

0.699

SPATA19

0.678

SLC24A4

0.663

NDUFS8

0.646

PAXIP1

0.634

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APRT	PPA2	ENSECAP00000022806	ENSECAP00000030804	Adenine phosphoribosyltransferase.	Pyrophosphatase (inorganic) 2.	0.807
ATP6V0A2	PAIP2	ENSECAP00000022132	ENSECAP00000009870	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Poly(A) binding protein interacting protein 2.	0.718
ATP6V0A2	PAXIP1	ENSECAP00000022132	ENSECAP00000015728	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	PAX interacting protein 1.	0.685
ATP6V0A2	PPA2	ENSECAP00000022132	ENSECAP00000030804	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Pyrophosphatase (inorganic) 2.	0.739
ATP6V0A2	SPATA19	ENSECAP00000022132	ENSECAP00000035022	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Spermatogenesis associated 19.	0.611
EEF1G	EIF5A	ENSECAP00000012558	ENSECAP00000008444	Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.	eIF-5a domain-containing protein.	0.744
EEF1G	EIF5A2	ENSECAP00000012558	ENSECAP00000020175	Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.	Eukaryotic translation initiation factor 5A2.	0.742
EEF1G	PPA2	ENSECAP00000012558	ENSECAP00000030804	Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.	Pyrophosphatase (inorganic) 2.	0.735
EIF5A	EEF1G	ENSECAP00000008444	ENSECAP00000012558	eIF-5a domain-containing protein.	Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.	0.744
EIF5A	EIF5A2	ENSECAP00000008444	ENSECAP00000020175	eIF-5a domain-containing protein.	Eukaryotic translation initiation factor 5A2.	0.892
EIF5A	PPA2	ENSECAP00000008444	ENSECAP00000030804	eIF-5a domain-containing protein.	Pyrophosphatase (inorganic) 2.	0.703
EIF5A2	EEF1G	ENSECAP00000020175	ENSECAP00000012558	Eukaryotic translation initiation factor 5A2.	Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.	0.742
EIF5A2	EIF5A	ENSECAP00000020175	ENSECAP00000008444	Eukaryotic translation initiation factor 5A2.	eIF-5a domain-containing protein.	0.892
EIF5A2	PPA2	ENSECAP00000020175	ENSECAP00000030804	Eukaryotic translation initiation factor 5A2.	Pyrophosphatase (inorganic) 2.	0.699
NDUFS8	PPA2	ENSECAP00000008039	ENSECAP00000030804	NADH:ubiquinone oxidoreductase core subunit S8.	Pyrophosphatase (inorganic) 2.	0.646
PAIP2	ATP6V0A2	ENSECAP00000009870	ENSECAP00000022132	Poly(A) binding protein interacting protein 2.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.718
PAIP2	PAXIP1	ENSECAP00000009870	ENSECAP00000015728	Poly(A) binding protein interacting protein 2.	PAX interacting protein 1.	0.566
PAIP2	PPA2	ENSECAP00000009870	ENSECAP00000030804	Poly(A) binding protein interacting protein 2.	Pyrophosphatase (inorganic) 2.	0.770
PAIP2	SPATA19	ENSECAP00000009870	ENSECAP00000035022	Poly(A) binding protein interacting protein 2.	Spermatogenesis associated 19.	0.655
PAXIP1	ATP6V0A2	ENSECAP00000015728	ENSECAP00000022132	PAX interacting protein 1.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.685