STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)    
Predicted Functional Partners:
ZFPL1
Zinc finger protein like 1.
      
 0.829
RAD9A
Cell cycle checkpoint control protein; Belongs to the rad9 family.
      
 0.822
PRXL2B
Peroxiredoxin like 2B.
      
 0.811
RIMS2
Regulating synaptic membrane exocytosis 2.
    
 
 0.798
ADSL
Uncharacterized protein.
      
 0.778
NINJ2
Ninjurin 2.
      
 0.763
LRTM2
Leucine rich repeats and transmembrane domains 2.
      
 0.739
SUCLA2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 
 0.720
DBN1
Drebrin 1.
    
 
 0.701
PRAME
Preferentially expressed antigen in melanoma.
    
 
 0.697
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.