STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INSM2INSM transcriptional repressor 2. (599 aa)    
Predicted Functional Partners:
SEZ6L
Seizure related 6 homolog like.
      
 0.823
SEC11A
Signal peptidase complex catalytic subunit SEC11.
      
 0.767
PEX11A
Peroxisomal biogenesis factor 11 alpha.
      
 0.764
LRRC7
Leucine rich repeat containing 7.
      
 0.697
FA2H
Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]
      
 0.634
ACOX3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
      
 0.630
USH1C
USH1 protein network component harmonin.
      
 0.624
NEUROD6
Neurogenic differentiation factor.
   
 0.614
CDH12
Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.572
PDX1
Pancreatic and duodenal homeobox 1.
   
  
 0.565
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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