STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPTXRNeuronal pentraxin receptor. (497 aa)    
Predicted Functional Partners:
CBX6
Chromobox 6.
 
      0.859
GRIA3
Glutamate ionotropic receptor AMPA type subunit 3.
   
 
 0.677
RNF2
Ring finger protein 2.
    
 0.673
RING1
Ring finger protein 1.
    
 0.673
PICK1
Protein interacting with PRKCA 1.
      
 0.635
CHGA-2
Chromogranin A.
      
 0.537
PCGF2
Polycomb group ring finger 2.
    
 0.535
LOC102148742
RING-type domain-containing protein.
    
 0.535
RUNDC3A
RUN domain containing 3A.
   
  
 0.534
CHGA
p-Glu serpinin precursor; [Pancreastatin]: Strongly inhibits glucose induced insulin release from the pancreas. [Serpinin]: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation.
      
 0.533
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.