STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HYIHydroxypyruvate isomerase (putative). (446 aa)    
Predicted Functional Partners:
GRHPR
Glyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.931
AGXT
Serine--pyruvate aminotransferase.
    
  0.900
AGXT2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
  0.813
DAO
D-amino acid oxidase.
     
  0.800
PARP8
Poly [ADP-ribose] polymerase.
  
  
 0.749
SKA1
Spindle and kinetochore associated complex subunit 1.
      
 0.742
TPT1
Tumor protein, translationally-controlled 1; Belongs to the TCTP family.
   
  
 0.713
PARP6
Poly [ADP-ribose] polymerase.
  
  
 0.706
PARP15
Poly [ADP-ribose] polymerase.
   
  
 0.637
PARP16
Poly [ADP-ribose] polymerase.
      
 0.636
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.