STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HELQHelicase, POLQ like. (1081 aa)    
Predicted Functional Partners:
FANCD2
FA complementation group D2.
   
 0.815
MCM9
Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family.
   
  
 0.811
RFWD3
Ring finger and WD repeat domain 3.
      
 0.780
MCM8
Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family.
   
  
 0.756
FANCM
FA complementation group M.
   
 
 0.740
POLN
DNA polymerase nu.
 
  
 
 0.731
SPO11
SPO11 initiator of meiotic double stranded breaks.
    
 
 0.683
MSH4
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 
 0.675
TLK1
Methyltransferase like 8.
   
  
 0.670
SHLD2
Shieldin complex subunit 2.
      
 0.650
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.