STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACSL5Acyl-CoA synthetase long chain family member 5. (683 aa)    
Predicted Functional Partners:
FASN
Fatty acid synthase.
  
 0.944
CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform; Belongs to the carnitine/choline acetyltransferase family.
   
 
 0.915
MGLL
Monoglyceride lipase.
  
 
 0.869
PPT1
Palmitoyl-protein thioesterase 1.
   
 
 0.843
PPT2
Palmitoyl-protein thioesterase 2.
   
 
 0.828
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
   
 
 0.828
ACSL3
Acyl-CoA synthetase long chain family member 3.
  
0.802
ACSL4
Acyl-CoA synthetase long chain family member 4.
  
0.798
PNPLA3
Patatin like phospholipase domain containing 3.
   
 
 0.789
CPT1C
Carnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family.
     
 0.776
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.