STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS2Suppressor of cytokine signaling 2. (270 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
   
 0.979
JAK2
Tyrosine-protein kinase.
    
 0.971
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.966
SOCS3
Suppressor of cytokine signaling 3.
    
0.953
SOCS1
Suppressor of cytokine signaling 1.
    
0.943
ELOB
Elongin B.
    
 0.939
IRS1
Insulin receptor substrate 1.
    
 0.929
IRS4
Insulin receptor substrate 4.
    
 0.923
INSR
Tyrosine-protein kinase receptor.
    
 0.922
IRS2
Insulin receptor substrate 2.
    
 0.915
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.