STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOX18SRY-box transcription factor 18. (383 aa)    
Predicted Functional Partners:
CLDN5
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.885
CCDC85B
Coiled-coil domain containing 85B.
    
 
 0.807
ZNF358
Zinc finger protein 358.
    
 0.763
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
   
 
 0.753
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.663
FOXC1
Forkhead box C1.
   
 0.656
LYVE1
Lymphatic vessel endothelial hyaluronan receptor 1.
   
 0.643
ROBO4
Roundabout guidance receptor 4.
   
  
 0.643
FOXC2
Forkhead box protein C2.
   
 0.608
CCBE1
Collagen and calcium binding EGF domains 1.
      
 0.607
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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