STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD45Ankyrin repeat domain 45. (288 aa)    
Predicted Functional Partners:
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.930
DNAJC10
DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
  
 0.924
HYOU1
Hypoxia up-regulated 1.
   
 
 0.917
SEC63
SEC63 homolog, protein translocation regulator.
  
 
 0.881
SIL1
SIL1 nucleotide exchange factor.
   
 
 0.868
SLC9C2
Cyclic nucleotide-binding domain-containing protein.
  
 0.824
BAG3
BCL2 associated athanogene 3.
   
 0.815
LOC100062428
Calreticulin.
   
 0.791
CALR
Calreticulin.
   
 0.788
RNASEL
Ribonuclease L.
  
 0.769
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.