STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FECHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (524 aa)    
Predicted Functional Partners:
FXN
Frataxin.
   
 0.980
UROD
Uroporphyrinogen decarboxylase.
 
  
 0.979
HMOX2
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
  
 
 0.965
COX10
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.
   
 
 0.947
HEPH
Hephaestin; Belongs to the multicopper oxidase family.
   
 
 0.939
HMOX1
Heme oxygenase 1.
    
 0.936
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
   
 
 0.926
UROS
Uroporphyrinogen III synthase.
  
  
 0.905
CPOX
Coproporphyrinogen oxidase.
     
 0.898
ENDOV
Endonuclease V.
  
  
 0.868
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.