STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIF4HEukaryotic translation initiation factor 4H. (277 aa)    
Predicted Functional Partners:
EIF4B
Eukaryotic translation initiation factor 4B.
   
 
0.951
PABPC1
Uncharacterized protein.
   
 0.930
EIF4A1
Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family.
   
 0.862
EIF4E
Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.
   
 0.811
EIF4A2
Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.
   
 0.806
RNPC3
RNA binding region (RNP1, RRM) containing 3.
   
 0.791
EIF4G3
Eukaryotic translation initiation factor 4 gamma 3.
   
 0.790
SNRPD1
Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
   
 0.789
EIF5
Eukaryotic translation initiation factor 5.
   
 0.782
POLR1E
RNA polymerase I subunit E.
   
  
 0.779
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.