STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISOC2Isochorismatase domain containing 2. (427 aa)    
Predicted Functional Partners:
IZUMO2
IZUMO family member 2.
      
 0.954
RASIP1
Ras interacting protein 1.
      
 0.908
NAPRT
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.879
PI4KA
Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.
      
 0.844
IZUMO3
IZUMO family member 3.
      
 0.799
IZUMO1
Izumo sperm-egg fusion 1.
      
 0.770
OPLAH
5-oxoprolinase, ATP-hydrolysing.
    
  0.736
NIT2
Nitrilase family member 2.
   
 
 0.718
NSUN5
NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
     
 0.713
INPPL1
Inositol polyphosphate phosphatase like 1.
   
  
 0.709
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.