STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTCHD4Patched domain containing 4. (904 aa)    
Predicted Functional Partners:
TMEM178A
Transmembrane protein 178A.
   
  
 0.858
CHRDL2
Chordin like 2.
      
 0.766
AMDHD1
Amidohydrolase domain containing 1.
      
 0.651
MFSD6
Major facilitator superfamily domain containing 6.
      
 0.563
TTLL5
Tubulin tyrosine ligase like 5.
      
 0.519
HIVEP1
Human immunodeficiency virus type I enhancer binding protein 1.
      
 0.487
GABRA6
Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.472
PREX2
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2.
   
  
 0.464
ORMDL1
ORM1-like protein; Negative regulator of sphingolipid synthesis.
      
 0.442
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif 12.
   
  
 0.437
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.