STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEATR5AHEAT repeat containing 5A. (2046 aa)    
Predicted Functional Partners:
IQCJ
IQCJ-SCHIP1 domain-containing protein.
      
 0.887
IQCB1
IQ motif containing B1.
   
  
 0.809
ARHGEF1
Rho guanine nucleotide exchange factor 1.
   
  
 0.767
TNS1
Tensin 1.
      
 0.685
HSD17B13
Hydroxysteroid 17-beta dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.632
AP1G2
AP-1 complex subunit gamma.
   
 
 0.615
SLC49A4
Solute carrier family 49 member 4.
      
 0.601
MBOAT7
Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family.
      
 0.539
AP4E1
AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
   
 
 0.532
TM6SF2
Transmembrane 6 superfamily member 2.
   
  
 0.532
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.