STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTOV1PTOV1 extended AT-hook containing adaptor protein. (415 aa)    
Predicted Functional Partners:
FANCM
FA complementation group M.
    
 0.725
JMJD6
Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.
      
 0.669
RBM23
RNA binding motif protein 23.
      
 0.661
AHSA1
Activator of HSP90 ATPase activity 1.
   
  
 0.517
AHSA2
Aha1_N domain-containing protein.
      
 0.515
KLHDC2
Kelch domain containing 2.
   
 
 0.506
PROM2
Prominin 2.
      
 0.472
APPBP2
Amyloid beta precursor protein binding protein 2.
   
 
 0.452
MED6
Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 0.442
FLOT1
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
   
 
 0.437
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.