STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHDC8AKelch domain containing 8A. (350 aa)    
Predicted Functional Partners:
CCDC18
Coiled-coil domain containing 18.
      
 0.637
RAB42
RAB42, member RAS oncogene family.
      
 0.569
PEX7
Peroxisomal biogenesis factor 7.
    
   0.495
GAS2L3
Growth arrest specific 2 like 3.
   
  
 0.493
GNG5
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
 0.493
KLHDC4
Kelch domain containing 4.
   
  
 0.478
GMPPA
GDP-mannose pyrophosphorylase A.
   
  
 0.450
LAMP3
Lysosomal associated membrane protein 3.
      
 0.443
KRT23
Keratin 23; Belongs to the intermediate filament family.
      
 0.433
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.422
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.