STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XRCC4X-ray repair cross complementing 4. (333 aa)    
Predicted Functional Partners:
LIG4
DNA ligase.
    
 0.924
KPTN
Kaptin, actin binding protein.
    
 0.832
SZT2
SZT2 subunit of KICSTOR complex.
    
 0.814
NPRL2
NPR2 like, GATOR1 complex subunit.
   
 0.772
NHEJ1
Non-homologous end joining factor 1.
     
 0.772
JMJD8
WD repeat domain 24.
    
 0.756
WDR59
WD repeat domain 59.
   
 0.754
DEPDC5
DEP domain containing 5.
    
 0.748
XRCC6
X-ray repair cross complementing 6.
     
 0.739
SPCS1
Signal peptidase complex subunit 1.
   
 0.739
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.