STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APPBP2Amyloid beta precursor protein binding protein 2. (593 aa)    
Predicted Functional Partners:
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.774
CUL2
Cullin 2; Belongs to the cullin family.
   
 0.703
FEM1B
Fem-1 homolog B.
   
 0.691
FEM1A
Fem-1 homolog A.
   
 0.677
SPOPL
Speckle type BTB/POZ protein like.
   
  
 0.653
KLHDC3
Kelch domain containing 3.
     
 0.653
KLHDC2
Kelch domain containing 2.
   
 
 0.652
RPS6KB1
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
   
  
 0.636
ZER1
Zyg-11 related cell cycle regulator.
     
 0.624
KLHDC10
Kelch domain containing 10.
     
 0.592
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.