node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADIPOQ | GCG | ENSECAP00000002024 | ENSECAP00000051685 | Adiponectin, C1Q and collagen domain containing. | Glucagon. | 0.566 |
ADIPOQ | GHRL | ENSECAP00000002024 | ENSECAP00000022644 | Adiponectin, C1Q and collagen domain containing. | Ghrelin and obestatin prepropeptide. | 0.732 |
ADIPOQ | INS | ENSECAP00000002024 | ENSECAP00000022114 | Adiponectin, C1Q and collagen domain containing. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.945 |
ADIPOQ | LEP | ENSECAP00000002024 | ENSECAP00000035337 | Adiponectin, C1Q and collagen domain containing. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.980 |
ADIPOQ | LEPR | ENSECAP00000002024 | ENSECAP00000012101 | Adiponectin, C1Q and collagen domain containing. | Leptin receptor. | 0.720 |
ADIPOQ | STAT3 | ENSECAP00000002024 | ENSECAP00000036035 | Adiponectin, C1Q and collagen domain containing. | Signal transducer and activator of transcription. | 0.436 |
CSF3 | INS | ENSECAP00000006754 | ENSECAP00000022114 | Colony stimulating factor 3. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.482 |
CSF3 | LEP | ENSECAP00000006754 | ENSECAP00000035337 | Colony stimulating factor 3. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.943 |
CSF3 | LEPR | ENSECAP00000006754 | ENSECAP00000012101 | Colony stimulating factor 3. | Leptin receptor. | 0.673 |
CSF3 | PRL | ENSECAP00000006754 | ENSECAP00000000120 | Colony stimulating factor 3. | Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation. | 0.905 |
CSF3 | STAT3 | ENSECAP00000006754 | ENSECAP00000036035 | Colony stimulating factor 3. | Signal transducer and activator of transcription. | 0.643 |
GCG | ADIPOQ | ENSECAP00000051685 | ENSECAP00000002024 | Glucagon. | Adiponectin, C1Q and collagen domain containing. | 0.566 |
GCG | GHRL | ENSECAP00000051685 | ENSECAP00000022644 | Glucagon. | Ghrelin and obestatin prepropeptide. | 0.945 |
GCG | INS | ENSECAP00000051685 | ENSECAP00000022114 | Glucagon. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.956 |
GCG | LEP | ENSECAP00000051685 | ENSECAP00000035337 | Glucagon. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.945 |
GCG | NPY | ENSECAP00000051685 | ENSECAP00000006719 | Glucagon. | Neuropeptide Y. | 0.566 |
GCG | POMC | ENSECAP00000051685 | ENSECAP00000013923 | Glucagon. | Melanotropin beta; MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes; Belongs to the POMC family. | 0.529 |
GHRL | ADIPOQ | ENSECAP00000022644 | ENSECAP00000002024 | Ghrelin and obestatin prepropeptide. | Adiponectin, C1Q and collagen domain containing. | 0.732 |
GHRL | GCG | ENSECAP00000022644 | ENSECAP00000051685 | Ghrelin and obestatin prepropeptide. | Glucagon. | 0.945 |
GHRL | INS | ENSECAP00000022644 | ENSECAP00000022114 | Ghrelin and obestatin prepropeptide. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.978 |