STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPARGC1APPARG coactivator 1 alpha. (839 aa)    
Predicted Functional Partners:
PPARA
Peroxisome proliferator activated receptor alpha.
   
 0.996
SIRT1
Sirtuin 1.
   
 0.992
ESRRA
Estrogen related receptor alpha.
   
 0.992
NRF1
Nuclear respiratory factor 1.
   
 0.990
FOXO1
Forkhead box O1.
    
 0.982
TFAM
Transcription factor A, mitochondrial.
     
 0.982
SOD2
Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.945
ENSECAP00000042890
Uncharacterized protein.
     
 0.945
GPX3
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.945
PRKAA2
Non-specific serine/threonine protein kinase.
   
 0.944
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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